There may be availability issue with tracking PE down and also some Profipack PE is not sold separately for Weekend Edition (case in point, Bristol Fighter, for instance). So the short answer - depends

My opinion on Eduard:
Older black box "Profipacks" from late 90's tend to be better than new "Profipack" from mid to late 2000's in terms of Photo-Etch, but visa versa in quality of styrene molding... Older black box "Profipacks" can be had on the cheap on Errhbae (bless you!), sometimes under $20 for some subjects - making those purchases quite attractive even when throwing out plastic... Though one must research each kit as parts included vary in between - it seems to be best of both worlds.
Weekend Edition only gives you 1 x aircraft scheme... WE, plus PE (Eduard or other aftermarket), plus decals gets a little pricey... I find Eduard 2 x aircraft bundles to be the best deals and Weekenders the worst for detailed builds.
Though I really hope the next Eduard production run of Early Aviation subjects takes a line from WingNut Wings example and elevates (and corrects where necessary) - or at least retaining the best of what has been produced in the past 20 years and correcting where necessary. Wishful thinking!