Hi Matt,
I always use spray. I use the testors flat laquer spray which has always worked well for me.
It may not make any difference and

I have never read the label, but I always use enamel paints. If you use acrylics just make sure the spray works OK for the kind of paint you use and spray a few very light coats so you don't get runs and drips. That will give you a really nice even coat.
ALSO... be sure to cover up/mask off all your clear parts. The laquer will totally cloud up these parts and that is not a pretty sight. You also will probably want to carefully remove the masks before the laquer totally sets up.
Post some pics when it is all done and good modeling,
Wayne